The two frenemies Anna and Vivien are now grown up and once they say goodbye to McGuffin Middle School they meet again at Kane High School, run by Principal P.J. Mayo. Although the two have always struggled with each other, things change when their parents get married and the two girls find themselves part of the same unlikely, odd, extended family. Between too sweet parents, crazy new relatives, big and small daily misunderstandings, the coexistence between Vivien and Anna is an impossible undertaking. How can they get rid of each other? What if instead of being sisters, they became partners? So they decide to found One Wish, a pink-share startup specialized in making people's wishes come true.