Exactly 12 months have passed and at the very best moment, the story between Marta and Arturo is over. “In love, opposites attract each other but in the end they break up” repeats Marta, who swears to herself that she wants to be alone for a while and continues to live with optimism with the disease that has always accompanied her. But when she meets Gabriele, a young designer who is as sweet and caring as he is funny and insecure, Marta acknowledges that he could be the soulmate she couldn’t find in Arturo. But before you get fully involved in a new story, it’s always best to be done with the previous one. Taking advantage of Gabriele’s temporary transfer to Paris, Marta tries to clear her mind with the help of her longtime friends Federica and Jacopo. While she is now more and more convinced to let herself go to a love story with Gabriele, the jealous boy makes an unforgivable mistake that will make them separate. When everything seems to go wrong, however, a phone call from the hospital changes everyone’s priorities: there is a compatible donor for Marta.